My daughter(5) has strep throat right now and my easiest way to get her anitibiotics in her is to take the syringe thing full of meds and squish it in as fast as I can and I always promise a small cup of whatever she wants to chase it down with, her pick milk,water,juice, whatever! She doesn't like this medication otherwise if it's something that she doesnt' mind the taste of I let her use the medicine spoon thing.
When she was a baby sometimes she enjoyed her meds other times I had to force them in. If I had to do that I would have her on my lap or somewhere I could hold her steady and put the syringe in her mouth and just do one big push of the syringe and then so she wouldn't spit it out I would catch her off guard and make a big noise or laugh or something to kind of shock her and get her attention somewhere else and she would forget about what was going on and just swallow.