I haven't worked full time for 12 years. My last job was at a great company, but it wasn't very family-friendly. It got to the point where my husband and I were fighting about who was going to stay home with the sick child(ren).
I don't have any regrets, but it was hard the first year. When I was growing up, all the kids were playing outside and the moms were standing around talking. I was sent over to a neighbor's house if my mom wanted to run to the store or school or whatever. Now all the kids are being driven around and people just don't seem so friendly. So I had to seek out other moms.
In 12 years I have never had a kid in school all day. I had one in kindergarten for about 6 months and then I had my youngest. I want to start working soon (need to), but really have no plans to return to what I did before. Everything was an emergency and there were no set hours, I always had to stay later at the last minute. That was another reason I quit.
I haven't figured out what I will do, but am thinking about just being a temp for now until I have a game plan.
In the end you have to do what's right for your family and not think about other people. Someone will give you the "I'm disappointed" talk and you have to blow it off. They aren't at your house with your family.