I have done several before. I first got my home biz bug back in 2006 with Beauticontrol. Great products. I still use them today. Nu Skin is another great skincare company, but the products are pretty expensive even with a rep's discount.
My most success was with a company called Noah's Ark Animal Workshop. It is like Build A Bear on wheels. Instead of having a store front, I went around to schools, camps, churches and childcare facilities. It was really fun and fit well with my skill set (I used to teach elementary).
There are many legit direct sales companies out there. I know people that do Scentsy and Party-lite (both candle and fragrance companies), Dove Chocolate and wine distributors. The biggest piece of it is realizing it is all about recruiting and booking parties to make a profit. I know people that have made very lucrative careers for themselves, so it is possible, but it is also a pretty demanding career too. Just remember you shouldn't have to put money upfront to pay for training or anything. Many will have you buy a starter kit of products to sell, but you should be able to sell it to earn your money back including a profit on top of it. If not, run the other way because it is most likely a scam. www.wahm.com is a good site to take a look at for all the different kinds of businesses out there. You can also get some sound advice from people there too. Good luck!
A.