It's okay if the house isn't spotless!! So just let yourself relax on that issue. Of course clean and spotless is nice, but it's not necessary. Then can the kids help? My kids have chores that they rotate weekly. Without their help, we couldn't function. They are all in activites and hubby and I both work full-time, so they have to help. They are chores they can do easily, but it helps my hubby and I tremendously!
I don't worry about the basement very often (it's finished, but it's the kids territory). The office is the front room in our house, but it's the last one I think the clean because I don't go in there often. I'd love to get in there and organize, clean, and restock it, but that will take time.
The kitchen is always okay, 95% of the time) clean. I grew up as one of 7 and the kitchen always seemed dirty, which drove me nuts. The kids also help with unloading the dishwasher and changing the trash, neither of which fall in line with their duties. Other than that, if the house gets to be too messy, everyone takes 30 minutes and we can do a quick clean.
I hope you find something that works for you, but really, if the house is a mess, you have to just let it go sometimes...even though it tends to stress me more.
Good luck!