M.R.
I lived in Missouri for eight years just outside of St. Louis and they don't call it the Show-Me state for nothing! There is plenty to see and do in and around the city and especially in the Ozarks but having such little kids does make it tricky. Some things that the five and eight year old will appreciate is the St. Louis Gateway Arch. Even if you don't have time for all the fanfare and going up inside the arch to the observation room, the hugeness and grandness of it alone is enough. See if you can park the car and stand close to the Arch itself. It's amazing! There's also the ever-famous Anheuser-Busch Clydesdales that are raised and kept in stables at the downtown brewing company. They are truly magnificent creatures and come with all the bells and whistles that these famous horses are so famous for! There are tours of the whole beer brewing plant but also tours of the horse stable as well. Once again...it is a kid- friendly favorite stop. Lastly, there is also the St. Louis Zoo which is also downtown as well. This would be more of a whole day affair but a beautiful visit and certainly a family-oriented place to go. I really could go on and on about the list of things to do in Missouri or St. Louis but these were the top three for me as a kid and certainly sights that I will never forget now as an adult. If you choose one single thing...go for the Gateway Arch. It is too magnificent for words!