J.S.
Not a man, but I have had three biopsies done on thyroid nodules over the span of six years. They have always come back normal/inconclusive
Having nodules on your thyroid is actually very common, and we just never know they are there. The only reason they found mine was because my regular doctor thought my thyroid felt "full" so they sent me for an ultra sound.
I actually have two thyroid tumors. One is 3.3 CM the other 1.4, they grow every year.
If they give you the option do the fine needle biopsy. It is over in like five minutes, not even kidding. The core biopsy took about half an hour and was by far more painful, and still came back inconclusive.
He will be sore for a couple days, but then should be fine.