Go through each room and "Clean Sweep" it. Make three piles...
Keep: items that you use on a REGULAR basis or that have substantial sentimental value (like your wedding album)
Toss: We use the "one year/ one touch" rule in our house... if it hasn't been used in one year, it's out. You pick it up, decide which pile it goes into and move on to the next item These items may end up in the "donate" pile depending on what they are.
Donate: Items that are in good shape, but are not useful to us any longer (newborn clothing, Boppy, my son's clothing, our clothing, furniture, serving pieces, etc.)
If your playroom is filled with toys, start there. What do your children actually play with? Are there toys that they have outgrown? Missing pieces? Not in great shape? Out they go. Then take a look at what is left and purchase some kind of organizational system to store them. I love the ITSO stuff from Target because it's inexpensive, but sturdy and looks pretty good.
In your guest room, consider how often you actually have guests who stay for more than 2 or 3 nights at a time. If you don't really have long-term guests all that often, consider getting rid of the bed and replacing it with a pull-out couch. That will free up space for a small table with chairs and art storage. Look through your crafting items and see if those can be stored/organized differently.
Our house is not cluttered. We both hate clutter and knick-knacks, but every year we go through our closets, the attic and the basement and purge more things. Every two years, in my opinion, is not frequent enough!
As for the coffee pot... I would again look at how often you REALLY use it. If you host company 2 or 3 times a year, I would get rid of it and buy a "box of Joe" from DD instead. If you have company on a regular basis, then store it somewhere.