This summer, I was involved in a "science Sundays" program for my son and his friends. Here's one of my favorite activities.
1. Boil some purple cabbage. You can then ether put the juice in teeny tupperware jars or dip strips of paper towel in the juice. Either way, you've got some homemade litmus paper / "litmus juice"
2. Bring a bunch of common, safe household acids and bases with you, along with the paper/juice. Baking soda, baking powder, and toothpaste are all bases; vinegar, citrus, etc, are all acids. AND, bring in a neutral substance (water) for a control.
3. Have the kids hypothesize which is an acid and which is a base, and then test it via the litmus. Record both the hypotheses and results on a big piece of butcher paper.
4. Then have them hypothesize what will happen if you mix acids and bases. Get hypotheses on all possible combinations (acid + acid, base + base, acid + base, acid + neutral, base + neutral). Then, test the combination.
5. Make sure you record all the results. 2nd graders may be able to do their own mini "lab reports"; for 1st graders, you may be better off with one big piece of butcher paper.
The kids should get a fun result (acid + base = "volcano), but more importantly, they'll learn the rudiments of the scientific method.