L.M.
Well it could be a slight allergy to either the bed itself or the detergent in the bedding. My kids are allergic to dreft detergent and you can only use ivory snow or homemade. Beds do have latex in them so you might try touching her with a latex glove (like a cleaning glove) and seeing if it happens where you touch her. If it does... well she is allergic , and it is time to invest in cover for her mattress (a zip on type is best) to make it so she can sleep on it.