K.D.
You should start noticing improvements sometime after about 6 weeks to 3 months, depending on how low you were and if you're on the correct dose. After a while, you'll be able to tell by how you feel if you need to adjust your medicine. I'm never wrong about when my dose needs to change, or how badly it needs to be adjusted. Just be faithful with your medicine, and do take it on an empty stomach. The body does not readily accept thyroid medicine orally, so the empty stomach is a biggy. Some studies show that as much as 80% of the medicine can pass through your body unabsorbed. Something that makes a difference for me, is I cannot take the generic. I know what they say, but I'm not the only one I know who says their numbers get off on the generic. If generic works for you, then go ahead and save the money. It works for my mom. You can't switch back and forth, though. They really work differently in the body. Any doctor or pharmacist should tell you that you can't switch on this one. (If they don't, I'd think about whether or not you want them taking care of your thyroid. This is pretty basic information). Having hypothroidism isn't too bad, once you're used to it. The medicine does a pretty good job for me. If you get pregnant again, it will be a roller coaster of med changes during and after for a few months. I usually have at least 2 if not 3 or 4 doses on hand to switch around. GL! Let me know I can help with any other questions. I've dealt with this for over 10 years now (and several pregnancies).