Peanut Allergy Cure

i have heard that if you start with alittle bit and then incress but why dose he need to eat peanut butter ? if you realy want proper answers unsult an allergey do. good luck A. no. hills

Hi M. I,

OK, this is techy talk:

Currently, there's no cure for peanut allergy, or technically any other allergy, although immunotherapy can increase tolerance to an allergen, which reduces responsiveness and subsequent symptoms. Peanut allergy, in particular, tends to be life long but apparently 20% children do outgrow it, according to the Dr. David Fleisher at National Jewish Hosptial in Denver, 50% of those with IgE < 5IU/mL will outgrow the allergy. (My daughter's didn't appear until early adolescence, however). I'm happy to see that no one has posted the snake-oil NAET therapy as yet. If they do, please ignore it. It is not based on sound physiological or biochemical research or knowledge and its proponents choose to self publish rather than submit their work to colleagues for rigorous review. QuackWatch recommend reporting NAET practioners to the States Attorney General for investigation of fraud and patient endangerment.

As for Jennifer's cure, I'm really glad that this worked for her son, but this only means that he was probably not truly allergic to peanuts. The allergens involved in true peanut allergy are all in the ara-H protein family that is specific to the peanut, and not to fungi that grow on peanuts. It is possible that Jennifer's son tested positive with a skin prick test, as these tests use allergen extracts that are not specific for the ara-H proteins. Some of the blood tests available are also not very specific and may detect contaminating allergens, but newer ones that are being developed use recombinant proteins and are highly specific.

I went out to Allergy, which is the journal of the European Academy of Allergology and Clinical Immunology (EAACI), and pulled the abstract for this study, which I've copied below. I'm going to borrow a copy of the journal from a colleague so I can read it in its entirety. If I can download it in pdf format or scan it in, I'll send you a copy if you like.

It is very important to understand that this was an extremely small study that included only 4 children, so the results are not statistically significant and may not be applicable on a wide scale. It does appear to offer hope as a pilot study, however, especially since, according to a recent WebMD article, it supposedly replicates the results of another small study conducted in the US last year (20 children, total, but I can't find evidence of publication or of a registered trial at clinicaltrials.gov). see http://www.webmd.com/allergies/news/20090220/peanut-flour... for the webmd article.

One thing that is important to note is that Allergy is a highly prestigious journal and most manuscripts submitted to it get rejected because they do not meet its very rigorous standards for research quality. The fact that this article was published in Allergy speaks volumes about it's quality and value to the field. On a separate note, another colleague will be travelling to the EAACI conference at the beginning of June. He has promised me that he will look for a poster presentation by Dr. Clark and see if he can speak to him about his trials and results. If anything comes of that, I'll let you know. Also, there are on-going trials using peanut flour oral immunotherapy that are recruiting at 5 sites in the US (none in California). Unfortunately, your son is too young to participate (minimum age is 12yrs), but Duke University looks like it's recruiting for trials in 1 - 6 yr olds.

Short communication
Successful oral tolerance induction in severe peanut allergy
A. T. Clark 1 , S. Islam 2 , Y. King 1 , J. Deighton 1 , K. Anagnostou 2 , P. W. Ewan 1
Departments of 1Allergy and 2 Medicine, Pathology Block Level 5, Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK
Correspondence to A. T. Clark
Department of Allergy
Cambridge University Hospitals NHS Foundation Trust
Box 40
Addenbrooke's Hospital
Hills Roads
Cambridge CB2 2QQ
UK
Copyright Journal compilation © 2009 Blackwell Munksgaard
KEYWORDS
anaphylaxis • desensitization • food allergy • immunotherapy • peanut

ABSTRACT
Background: Peanut allergy is common, potentially severe and rarely resolves causing impaired quality of life. No disease-modifying treatment exists and there is therefore a need to develop a therapeutic intervention.

Aims of the study: The aim of this study was to investigate whether peanut oral immunotherapy (OIT) can induce clinical tolerance to peanut protein.

Methods: Four peanut-allergic children underwent OIT. Preintervention oral challenges were performed to confirm clinical allergy and define the amount of protein required to cause a reaction (dose thresholds). OIT was then administered as daily doses of peanut flour increasing from 5 to 800 mg of protein with 2-weekly dose increases. After 6 further weeks of treatment, the oral challenge was repeated to define change in dose threshold and subjects continued daily treatment.

Results: Preintervention challenges confirmed peanut allergy and revealed dose thresholds of 5–50 mg (1/40–1/4 of a whole peanut); one subject had anaphylaxis during challenge and required adrenaline injection. All subjects tolerated immunotherapy updosing to 800 mg protein and i.m. adrenaline was not required. Each subject tolerated at least 10 whole peanuts (approximately 2.38 g protein) in postintervention challenges, an increase in dose threshold of at least 48-, 49-, 55- and 478-fold for the four subjects.

Conclusions: We demonstrated a substantial increase in dose threshold after OIT in all subjects, including the subject with proven anaphylaxis. OIT was well tolerated and conferred protection against at least 10 peanuts, more than is likely to be encountered during accidental ingestion.

No, but I have friends that used to be allergic to cats and other things and after an organic vegetable fast for 30 days, they are no longer allergic. And, of course, the amazing weight loss.

I know kids can possibly outgrow milk allergies, but not sure about peanuts.
All the best!

Hi:

You may want to look into having your child's allergies cured via NAET. I have had many allergies cured in this manner as have two of my grandchildren. I love my doctor (Dr. David Karaba at East West Medical Group in Fullerton) and I am certain that if you told him I sent you, he would give you a free consultation so that you could learn more about it and then decide if it was something you wanted to pursue.

Best wishes,

M. Sexton

I read an article that said doctors can overcome the peanut allergies, but it takes weeks or months of doctor supervised visits... Or, with your next child, try introducing peanuts earlier, like when they first start eating... That is what some doctors have started recommending...
Good luck
R.

My son was literally almost deaf due to fluid in the middle ear from his peanut allergy. Even stopping peanut butter didn't work, so we actually did a homeopathic remedy for fungus, since there is a fungus attached to peanuts and this rid the body. After fighting this for 3 years, it took him 4 months on the remedy, but his ears cleared up completely and now when he has peanuts, there is no noticable issue, but I do give him PB8 when he has them...it's an awesome probiotic to keep his system balanced.

Toxic Fungi Mold Nosode from Professional Complementary Health Forumlas, but they are only sold through holisitic doctors.

I would look for an osteopath dr or one that can prescribe chelation. Read the book "healing the childhood epidemics....." by Kenneth Bock.

They are working on a desensitization program for peanut allergy. They start out with like a fraction of a molecule and gradually work up. Unfortunately, it is not a cure. Basically, they've been able to desensitize a child to the point that if he accidentally ingests a product with peanut in it, he won't die. I think the most a child has been able to consume is like 7 peanuts. So it's definitely not a true cure, because it won't give you carte blanche to eat peanut butter. But it's worth looking into getting into one of the studies if it will make things safer for your child.

Hi M.:
I'm A little surprised,that you don't look at the peanut flour method as more than merely a glimmer of hope. Every child they have tested this on has over come their peanut allergy.What else are you looking for?

My son's allergist didn't give us much hope that his peanut allergy would ever go away so I am now dealing with it. It is hard and I hope one day the peanut flour method will be available to all people. It is very scary but my son is two now and we have survived without the use of the epi Jr pen.!! Please do not give your next child peanuts early like a previous person wrote. My son never had a peanut and is highly allergic. He probably got it from me when I breast fed. Good luck !!