Norovirus

I don't know whether you're more interested in killing the virus, or removing the stain. Since norovirus is so extremely virulent, I strongly suggest disinfecting BEFORE you clean. I wouldn't worry too much about leaving a stain, because it will be covered.

I can't tolerate chlorine bleach odors, so I looked up other appropriate disinfectants. Hydrogen peroxide was listed as effective, so I used some chorine-free laundry bleach, a stronger hydrogen peroxide formula than the medicine-cabinet stuff, in a spray bottle. I used that on every surface I might have touched after having a bout of the nasties last month (was exposed while trying to help my mom deal with explosive diarrhea – omg!!!)

The hydro-perox worked beautifully – nobody else got sick. It's a superior disinfectant for multiple uses. I clean my countertops and doorknobs with it any time the flu, norovirus or other contagion is going around.

Be aware than this product is a strong oxygen bleach, and can have a bleaching effect on some fabrics/surfaces. But that oxygen literally burns the viral cooties to death (while breaking itself down harmlessly into oxygen and water). I'd saturate the affected area, and lightly mist the rest of the mattress. Wait several minutes, and then use a hair dryer on any spots that are excessively wet. (Be careful not to breathe the mist as it can damage the surface cells in your lungs.)

Wishing your household good health. This illness is so utterly miserable.

I have this pet stain remover that I use on vomit. It has enzymes that help with that sort of thing. I have also used a mixture of (equal parts) hydrogen peroxide, baking soda and a touch of dish soap. I have a Bissel Little Green Machine that I can use to steam clean as well. All of these work equally well.

I understand your concern.. I don't know how long norovirus can persist in the environment.

Can you turn the mattress over to prevent anyone else coming in contact with it?

All the websites I checked said to wash bedding in as hot of water as possible, and clean surfaces (toilets, etc) with a bleach spray. Unfortunately, I don't think you can do that with the mattress.

http://www.about-norwalk.com/outbreak-control-guidelines.pdf

Here's a link.... on page 5 it says "Mattresses should be thoroughly aired in bright sunlight. Soft furnishings should be placed in bright sunlight for a few hours. All mattresses and soft furnishings have been contaminated by
vomit should be removed for steam cleaning."

It also says that it can persist in the environment (carpets, etc.) for 12 days or more.... scary!

I'd have to wash it then spray it with Lysol spray. I don't have money to buy a whole new mattress just because it got dirty.

I would use my Spot Shot carpet cleaner I use for pet accidents, spray on and scrub w/ sponge. Then I would take my steam mop as it has an attachment to glide over carpet/mattresses. Then I would spray Lysol on it.

Honestly, depending on how much of it got on the mattress and how big of a spot I would probably have it professionally cleaned. I would be concerned about any smell. If you do it yourself an enzyme cleaner for pet stains would probably do the trick.

Updated

Honestly, depending on how much of it got on the mattress and how big of a spot I would probably have it professionally cleaned. I would be concerned about any smell. If you do it yourself an enzyme cleaner for pet stains would probably do the trick.