Hi L. C.
First, I'm going to move away from the word "respect"-- as other posters have said, they have no concept of what the word really means (at least, not in the identical context we adults have).
You've already gotten some good advice, and I'll give you a list of what works for me (with my old toddler/preschoolers and my son at home)-- some things might be repeats of previous posters, but it bears repeating:
1. Make sure, first and foremost, that adult items are stored only where adults can access them. Keys, cell phones, wallets, purses, computers-- all out of reach unless the child(ren) is reliable on leaving them alone. This is our responsibility as smart adults.
2. Have consistent rules. This means that coloring ONLY happens at appropriate places; at the table or at a little art table within supervision. This means that children sit and eat/drink ONLY at the kitchen table. My son is allowed to have water in the bathroom, but if he takes it into his room (and he has) the privilege is lost until he earns it back by showing responsibility in other areas. In the car, only dry foods (crackers, almonds, not-overly-gooey PBJs, string cheese...no open-container yogurt, etc. and nothing sticky.) and only water. If you have young children, the car is not a place for messy food. And stickers--- ugh, stickers should have ONE place they can go. In our home, stickers may not be stuck on anything other than paper or a little set of plastic drawers he stores his coloring books and some other toys in. In other words, 'disposable' furniture.
3. When they make a mess, they must help clean it up immediately. (Example; when my son spills, he has to stop and clean it up with a rag. I do the follow-up.) If they mark on a wall, they help clean it up, etc.
4.Anything that's already a "known no-no" means that there's a consequence; this could be NOT using that item for a few days or a loss of privilege. (When my son was sneaking water into his room and hiding it, we decided that he would lose his half-hour of 'staying up after bedtime stories' privilege for a week. Our explanation to him was that he wasn't behaving like a big kid and following the rules, so he had to go to bed at the earlier time for a week because staying up was a 'big kid' treat. We have had NO more problems with this since then.)
4. Supervise any and all art supplies. Crayons, scissors, bendaroos, playdough, silly putty, markers, pens-- anything like that needs to be on an "asking" basis, and stored where they cannot access them independently. Items not being used correctly are removed from use.
5. Decide what the consequences are ahead of time, so you aren't in PO'ed reaction mode. If my son trashes a toy by writing on it-- wow, that's too bad it looks so yucky now. Hmmm. Any broken toys--either he helps repair it, or we throw it away.
6. Decide what's important to you. For example, some families let the kids jump on the sofa and beds. We do not. Jumping on the sofa means you may not use it for the rest of the day. Jumping on my bed means you may not go in my room. Hanging on the cupboards means that you don't get to be in the kitchen for a while, until you've done a chore or two.
Lastly, I make sure that my son doesn't go off to play after art or eating until he's washed his hands.
All of this means that I have to be fairly on top of the kids in regard to discipline and paying a lot of attention to them. Maybe having a gate between your kitchen and the rest of the house would help, and then all art supplies and food/drink stay in that space. Sometimes, blocking off that traffic when they are running out of that room in particular gives us a moment to catch them and stop any further mischief. With three kids, I would definitely have some strong rules for use and some sort of routine habits for cleaning up and taking care of things.
Don't forget-- at three and five, your bigger children can help you take care of the house. If they are invested in taking care of things, it's easier to get them interested in keeping things nice.