My 15 month old was prescribed Pediasure because she only weighed 17 pounds. She has always been smaller, was born at 5lbs 13 oz, and has always gained consistently, just always been smaller. I gave her three bottles of Pediasure a day and she lost all interest in solid foods. She used to eat bananas, yogurt, cheese, etc, and refused all solids after about a week on the Pediasure. So, of course, she did not gain weight, she didn't lose, but she didn't gain. So doctor insisted 4 bottles of PS a day (do you know how expensive that is?) and I could never get her to drink more than 3 oz at once, and when she was finished she would gag and sometimes throw up. One day she kept throwing up...we ended up in the ER because her blood sugar level had dropped too low and she was almost unresponsive. Doctor insisted more Pediasure. As parents we'd had enough. We put her back on Similac Go and Grow baby formula and she drank 8 oz, she immediately got her appetite back and eats 4 small meals a day now. She is healthier now than she was at 15 months. I firmly believe Pediasure is not the right thing for some kids. It is full of sugar, thick, and hard to digest. I think it was making my toddler sick and she had no desire for real food. The smoothies are a great idea!