Depends on what the plush is made of and it's original texture. If it looks and feels melted then nothing can be done. I'd try wetting it and then put it inside a pillow case with a fabric softener sheet and drying it again on low. Put it in with other clothes. A couple of dry bath towels or a regular wash so that it gets plenty of movement.
My granddaughter has a teddy bear from the Dollar store. She vomited on it and it had to be washed. It's plush was 1/4" long and thinly dispersed. It did not wash/dry well and looks quite scraggly. It's become her favorite stuffed animal. She told me he needed lots of love because he got sick.