R.J.
Absolutely.
Mirena, just like pills/patches/rings/shots/implants are all hormon based.
Hormones have a number of functions in the body, and they have a number of side effects.
Because our neurochemistry is all different, or cognitive emotional reactions to chemicals (including hormones) ALL vary, but usuall in similar ways.
For MOST people hormones affect mood (and several other things / aka common side effects. But as far as mood certain hotmones usually trugger certain mood effects in MOST people. Oxytocin, is a hormone, that is linked to "bonding" emotions in MOST people. Estrogen & Progrsterone are linked more toward "crankiness" in MOST people.)
For MOST people, the lower the hormone level, the less it causes side effects.
What's up with my caps lock on MOST?
In SOME, birth control hormones trigger uncontrollable rages and even delusions (PMDD). In SOME, birth control hormones trigger suical despair. In SOME birth control hormones trigger euphoria. In SOME, they equalize mood swings that exist without them. In SOME they trigger sex drive. In SOME they trigger gynecological cancers.
In SOME, lower levels of hormones trigger the above, but higher levels don't trigger a durn thing. (In MOST, remember, its the opposite; Lower levels, or localized levels... Like with IUD or Ring... Cause fewer side effects than pills or shots).
MOST v SOME
It sounds like you're in a "some" category.
As in, you either respond badly to lower levels, or you respond badly to local levels, or the pregnancy changed your neurochemistry & you can't tolerate BC hormones at all.