I agree with Erin T about parenting and children's behavior 100% and about the quality of the daycare setting. However, I also lean toward the side of saying that it IS best for kids to be at home with one parent. It is a constant pull - I want to be a SAHM but I also want to continue my career. I was in grad school for all of my 20s and had my first child at 31 and went from full-time to part-time work, so my career is not exactly moving ahead at lightening speed.
So I am really torn. Part of me wants to say, stay at home and enjoy them while they are young. And part of totally understands your desire to work. Honestly, I guess you can take the job and see how it works for you. Mentally committ to some period of time, and at the end reevaluate - like six months.
It may be corney, but try making a list with what you want not just in terms of career fit and professional growth, but also child care, time off, benefits, and hours/schedule. See how this job matches up.
I am very lucky to have a great situation - I work 16 hours per week, some from home, in the field I was educated in. In all honesty, if my employer had not been agreeable when I pushed for it, I probably would have quit. But I had a newborn at the time, so my perspective is different.
Whatever you choose, good luck. Just remeber, no decision has to be forever - change jobs, go back to being a SAHM, change child care, whatever - there is no reason to feel trapped by any decision.